If you want to really reach out there and bust a varmint especially when the wind gets up the 25-06 is the one I would pick. When it comes to deer the 25-06 is my favorite. I have killed well over 100 with a 25-06 and can count without taking off my shoes the ones that have taken a step after taking a 117 gr Sierra Pro Hunter from point blank out to a little over 500 yards.