I have five loads on my .223 Remington Brass and it's still usable. My loads are on the mild side. My loads are 24.5 grains of H335 with standard CCI or Winchester primers.
I bought 1000 of the once fired from brassmanbrass and have had no problems with near max loads of BLC-2 and CFE223. As of now they are on the eighth cycle of fire, tumble, small base resize, tumble, load. They seem fine to me.