Like green 788, i too use retumbo (89.0grns) with the 300 grain Sierra Match Kings with .5 minute or better results.
For 250 grain SMKs I use 86.0 grains of H4831SC.
For 250 grain SMKs I use 86.0 grains of H4831SC.
It sounds like it's already doing very well. Flyers 2 inches to the left of a 1.5 inch group at 400 yards can easily be explained by a tiny amount of wind you didn't see (about a 3 mph wind would do it)... or just the trigger pull or bi-pod loading (pushing harder against one leg than the other) could do it... it's hard to say for sure. Seating depth adjustments can reel in flyers in many cases too.
I've used Retumbo in my 110BA, and it has done well. I've shot the 300 grain Sierra Matchkings as fast as 2800 fps (with 92 grains of Retumbo), and that was a very accurate load. But due to pressure signs (flat primer, ejector swipe) I decided to drop the charge to 89.3 grains in Lapua brass, and it works very well also. That gives 2700 fps.
I tried that load at 600 yards just yesterday...
This was the load with a cold clean bore shot. My rifle is at around 120 rounds as of now, still breaking in... and it likes at least 2 fouler shots before it starts 1/2 MOA accuracy. My first fouler shot from a cold clean bore goes about 1/3 MOA low, and slightly right. (see 100 yard target below). I had 3 to 5 mph winds on the 600 yard target, and the low shot in that group was the second shot from a cold clean bore. I don't know why it printed left (wind, or just me)... but low for that shot is the norm in my rifle.
The guys reporting that Retumbo is temperature sensitive are just running their loads too hot. They switch to another powder that won't let them run so fast and they say "voila, this powder isn't as temp sensitive." But Retumbo isn't all that temp sensitive either if you're running sane pressures...
Dan