85g Speer btsp with R#19 & IMR 4831, Win brass is all over 3400 fps in a 26" barrel. The 85g Speer btsp is a deer bullet, not a varmint bullet with a pretty good BC. HV100 would be my second choice with speed and accuracy. Varget = IMR 4064 worked extremely well, but 200 fps slower than the above loads. IMR and H4350s worked very well. H and IMR 4895 are stellar, just not the speed of 19, IMR 4831, and HV100.
You rarely ever hear it mentioned, but the Barnes 80g TTSX is one heck of a deer and hog bullet and HV100 gives blistering speed with accuracy jumping .050 from the lands.
I got better penetration with the 85g Speer vs either of the Sierra 85's.