For 500 and in, deer and hogs, I would load Speer BTSP in 150 or 165 grains or 168 A-Max, H4350 is a superb choice for all of them though with the 150 I would definitely try Varget as well. All three of these bullets are very accurate, easy to load and kill extremely well. They are also some of the lowest price bullets out there so you can afford to shoot a lot. Sierra Gamekings are also very good, but cost considerably more than the bullets I previously mentioned. I don't see the need to try to make a '06 into a magnum or complicated loading, they typically shoot really well without a lot of work and good old cup and core bullets work amazingly well at normal '06 speeds.