A lot of wisdom here. I would chamber new untouched brass to see if the brass needs full-length sizing, which would indicate your headspace in the rifle is on the short side, which is no big deal big deal, bump the shoulder back a tad..A bushing then mandrel is standard for cases I use, new or fired.
A few necks will be flattened normally in new bulk brass, so at least I get them all round starting off.
As others have mentioned, you may have an issue with thick necks, which would mean that when you chamber the brass, the neck in the chamber is trying to swedge down the diameter of the neck which can lead to some incredible pressure spikes.