Read your manual and then read it again. Familiarize yourself with the process and pay attention to your details. Make sure your primers are seated fully, that you charge each case with powder once and visually inspect all cases for powder before you seat your bullets. The loads listed are generally safe, but you want to start below the maximum and slowly work your way up. Small cases are much more sensitive to overcharging with powder than your large calibers. Stay focused and have fun, I've been at it for thirty plus years and still have much to learn. I've never had much trouble getting decent accuracy from Hornady, Sierra and Nosler bullets, but I'm pretty new to loading for long range. There's a big difference between 300 yard accuracy and 1000.