If it's a 243, would the OP be using this for varmint hunting any? I think that changes whether or not you use MPBR. I personally don't like anything other than a 100 yard zero. Nothing will relegate a gun to safe duty quicker than missing an 85 yard shot on a coyote with your buddies watching. Nothing will Make you more confident with your rifle than a successful head-on dome shot on a coyote at 100 yds. At least at 400 yds I may have an excuse for a miss.
Another thing i have found to be of utter importance is cold-bore zero. Most factory rifles cold bore shot is an MOA off one way or the other. Not too big of a deal for 100 yd shots but will come into play at 350-400. We usually have a warm barrel by the time we get our rifles "sighted in" at the range. It's important to let it sit and then try again once the barrel is completely cool again.
Most of my hunting guns wear duplex reticles. I like to figure out how many MOA the bottom of the duplex is, translate that to yardage with a 100 yd zero and use that as my gauge.
