I don't see any opportunities in my near future for any hunts where I will need something special. I might harvest one doe a year, .243, .270 or 30.06 will work for the harvest. Heck even the .223 will for these little Texas deer. I only need 5 rounds. 3 to confirm zero and two for the hunt, just in case.
If a real hunt came along, I have 200 rounds 300WBY loaded with Nosler AB and PT (half and half) all with RL22.
For now I just keep playing with 22LR, both pistol and rifle. Heck, I can shoot 5.7x28 in a rifle for the same price as 5.56 and its more fun.