Just a couple days ago I asked Hodgdon for understanding of the numbering scheme and differences between H4895/IMR4895 & H4350/IMR4350.
Their reply:
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Those numbers refer to performance specs and are generally military based.
They are quite different.
They are made on different continents, have different chemistry, different granule size, different burn speeds and use different data.
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That IMR powders are now 'extreme',, could be, given that this is likely no more than made up merchandising with no actual basis provided by Hodgdon. I pay no mind to the extreme hogwash and focus only on my results with these powders.
I've also seen testing where IMR tested more temp stable than Hodgdon, and my IMR4350 is SLOWER than my H4350.
Anyway, IMR & H are not interchangeable. If you have a great load with IMR, buy a barrel-lifes-worth of that lot so that you can hang onto it.