Growing up my Dad used the 721 in 30-06 with leupold scope. My uncle and there huntin buddy both went through different calibers and manufactures but that's the only rifle my dad ever used and harvested his fair share of elk and deer and I never heard him mention any issues. He ended up giving me the rifle and the only issue I ever had was from poor maintenance the bolt got so dirty the firing pin wasn't striking the primer off so I took it too a gunsmith and they took the bolt apart and cleaned it and it also re-blued the gun and it's been great since. I own a few rifles but the machining and bolt action on the 721 is by far the tightest smoothest action of any modern rifle I've had my hands on. The only thing I'd change on it which is something I've never even looked into but I'm sure there's options out there is the trigger. It's a little heavy for me but that's it. My humble opinion is it's a great reliable rifle.