I handload ~ 65 cartridges, and the only one I use Cream of Wheat, 10 gr of any pistol powder, and no bullet is on is 257 Roberts Ackley Improved that I mistakenly headspaced like a 257 Roberts. If I do not use Cream of Wheat, the pressure is too high, it stretches too much, and case will not form right.
The next 3 rifles we built in that cartridge for friends were headpaced .004" shorter, and do not need the extra COW [Cream of wheat] step. They get a bullet on the first firing.