I spend quite a bit of time setting up my LRH rifles for the best compromise of pull length, comb height, and grip angle. Over several years I have found that the most demanding LR shots have generally been taken from a prone position with F/R rifle support in colder weather using heavier clothing. This positiom/condition gets priority with eye relief, cheek weld, and a more vertical grip style that can offer an elbow down/straight wrist shooting position. Once this base set-up is determined, I will check the rifle for fit from more upright positions, less clothing, etc, and make small adjustments as necessary. I've found that I usually have enough margin in the adjustment range to maintain the right prone condition, while accommodating an upright shooting position. Concerning LOP, I would err on the side of being too short over too long.