I was inquiring about the same with different grooved barrels. Especially the differences between a 5R and 6 groove barrel for a .338.
I read a post by "Frank" of Bartlien Barrels. He indicated no real advantage between 5/6 groove.
Found it:
Twist rate and groove number ? - SnipersHide.com Forums - Scout
The number of grooves for the most part doesn't mean #$%# when it comes to accuracy and or barrel life. Anybody telling you differently is either selling something or doesn't know what they are talking about.
The only exception I will make is in regards to 6mm bullets. If your building a 6ppc benchrest type rifle and your only going be shooting 70gr. and lighter bullets.....those light weight bullets don't like the 5R style rifling. Why? Because of the short bearing surface on the jackets. The rifling/lands do the driving on the bullet and I feel the 5R doesn't bite those short jacket bullets good enough. Those short jacket bullets and the 5R rifling will shoot upper .2xx's to a flat .3xx but nothing better that that and on a short range bench gun that won't win you any matches. So for those bullets I tell guys go with conventional rifling. This is where the lands meet the grooves at basically a 90 degree corner. I don't care if it's a 4 groove, conventional 5 groove, 6 groove, 8 groove etc...I've got a conventional 5 groove on my 6ppc gun. It will agg in the mid .1xx's at a 100 yards. Has shot groups in the .0xx's as well.
Now staying with 6mm and going to and if your shooting long heavy bullets like the 105gr. etc...then I go with the 5R. The odd number of grooves/lands don't directly oppose one another and in conjunction with the angles on the sides of the lands I feel the rifling will not distort/upset the bullet jacket as much and there fore helps fight bullet failure. Bullet failure is more of a problem for a long range shooter than a short range shooter.
I've shot barrels in everything from 2 groove up to 8 groove in calibers from .22rf up to .338 and I don't see a difference in accuracy other than the example I listed above with the 6mm's.
We've made accuracy test barrels for ammo makers, bullet makers and the gov't arsenals in .308win. with 4 groove and 5R. Also for .300wm in 4 groove, 6 groove and 5R rifling and .338 Lapua in 6 groove and 5R and all testing has shown no difference in real world accuracy.
Hope this helps!
Later, Frank
Bartlein Barrels