Sampson
You would be surprised as to what you will find when shooting your loads over a Chronograph.
Even weighing the brass out as close as possible really don't mean much. To get the true shooting accuracy from the cases, they MUST "all" shoot within around 10 to 15 FPS extreme spread and closer is better.
This is checked at 100 yards and when you get the ES close, you will see the group will tighten up.
If your a 1000 yard target shooter, this procedure is a MUST.
The cases and loads MUST match for extreme accuracy.
For LR Hunting and with a spotter shot first, this extreme is not as critical unless you want to have the best accuracy as possible.
Normally we boost the load for winter time LR hunting to buck the higher winds encountered in the mountains. A spotter is the key for this style hunting.
Later
DC