They just blew one of those Savages up (same website). Personally if I had a smokeless ML I'd stay away from pushing it as I don't trust the technology yet.
You can do pretty good with Triple 7 powder. As soon as I finish pillar bedding my Omega in a couple weeks I'm going to attempt to tune up a 500 yard load. 300 was a piece of cake. For hunting deer-sized game you're pretty much limited to 400 yards, even with smokeless, because the bullets aren't efficient enough to carry sufficient energy that far.