Have never hunted them, but have bumped into the big coastal brownies several times while fishing the streams for salmon. Those bears are BIG!
Wasn't there a story a couple of years back of one taking several hits from a .458 Win mag and still trying to get to the hunters? Brutally big, strong animals.
I'd think a .375 would be decent bear medicine - but what do I know? Also, I imagine there's a difference between hunting one, shooting at 100 - 200+ yards, and knocking one down when it's attacking.
Love reading about them, and even enjoy watching them on the salmon streams, but in reality, I'll likely not be able to afford the price of a non-resident guided hunt for one of those big beasts. You guys who hunt them - keep on posting. Those are some great photos!
Regards, Guy