I shot a big boar back in 2000 that tipped the scales at over 350lbs without his head. The hoist wouldn't lift him high enough to get him off the ground to weigh. We cut his head off and he bottomed out the scale.
I shot him with a 450 Marlin Ultra rifle, he ran about 45yds away and you could see the air steam out of both sides as we thought he had expired. I walked towards him and he came to life and charged, I launched a second round into his skull between the eyes, he kept coming, I side stepped him reloaded and took a shot as he turned, hit him but he still charged again, I side stepped again and reloaded, waited for him to charge again, side stepped him and put the barrel close to the side of his neck and pulled the trigger, he went down. I put three Hornady 350gr Interlock FPs into him before he fell permanently, the one between the eyes dug a trench to the skull and cracked it, but never penetrated. I haven't shot one between the eyes since with any caliber or bullet.
I have seen guys locally gashed on their lower limbs, tripped up, fallen and hurt because of poor decisions.
Generally they bolt at the first scent or sound of humans, but you put them in the right situation, you'll quickly find yourself in the wrong situation.