RL26 is a medium-slow powder, and unsuitable for the .308. Go with CFE223. RL26 is recommended for 300WM and the other Magnum cartridges, and for the 30-06 with 180 and above bullets. IMR 4064 is also a good powder for the .308. CFE 223 is showing at least 75fps increase over varget and the other recommended powders listed in the 2019 Hodgdon manual, though. It would depend on what you're going to shoot it in, though. But if you want more horsepower, don't try to turn the .308 into the 30-06. Just get a Ruger in 30-06. Take a look at the 30-06 and Superperformance as an example. It does to the 30-06 what CFE223 does to the .308, giving it about another 100 to 150 fps over conventional powders. If you're going with a 20 inch barreled .308, though, CFE223 is the way to go. It will duplicate conventional powders and velocities in 22 inch barrels through a 20 inch one. I wouldn't use it in a semi-auto until I talked with Hodgdon, though.