I am a big proponent for the GunWerks rifle systems as I have several of their rifles (two 6.5CMs, one 7mm RM, and one 6.5 PRC). In 2017 I took a GunWerks rifle with the new Clymer stock (titanium action) to Canada for a multi-species hunt. The rifle was chambered in 6.5 CM and was topped by a NXS 2.5-10x42 scope. The total weight of the rifle with scope was 7 pounds 10 ounces. During the 22 days I spent in BC, I was able to harvest a Stone Sheep, Mountain Goat, and Caribou. Shots varied in range from 160 yards to 485 yards. While a lot of folks will laugh at the 6.5CM, the sheep and caribou took one shot each, whole the mountain goat took 2 shots (I used the Berger 140g VLD bullets).
Since then I've purchased an updated rifle (Clymer 6.5 PRC w/18in carbon barrel, Leupold Mark V 3-18x44 scope) which weighs in at 7 pounds 8 ounces. When I went the 6.5PRC wasn't even a consideration, but I did have a 7mm RM which I considered. The 7mm RM was over a pound heavier but since I was backpacking in, I wanted to reduce weight and chose the 6.5CM.
I currently have a new GW rifle on order (the cut rifle in a 7SAUM which will weigh 6 1/2 pounds with optics) which I will take on a Dall sheep hunt in 2022. I ordered it with the 7SAUM as I will also be going after moose and grizzly.
I would recommend you order your rifle with a carbon fiber barrel which can be shortened to maintain stiffness/accuracy while reducing weight. The caliber is up to you and depends on what you plan on taking. If you are looking at grizzly I would suggest the 7SAUM or 7RM.
Regardless what GunWerks rifle you select - you will love them and how they shoot.