My solution for western rattlers is a Ruger LCR-X (3" barrel) and handloaded shotshells with 8 1/2 or 9 shot. I patterned several different size shot at 7yds. and these worked best in my pistol with a high pellet count on target. Pistol is light and has better sights than most pocket revolvers. Also has 5 shot capability. For gators, hogs, pythons, etc - use a much bigger gun !