Seating is magic to me for sure.
From what I've seen, and consistently, seating is the largest single reloading adjustment to accuracy (far more than powder).
Interesting(to me) testing results led me to 8thou OTL for best initial CBTO with a 6.5wssm Imp/139Laps. I could shape grouping with +/- 3thou, but beyond that window grouping flat out opens from 1/4-3/8 to 3/8-1/2moa at various distances.
This is interesting to me because it's the sharpest seating window I've run across.
This is not a problem, my seating with qualified ogives/inline dies is perfect and every round is always verified. I remained at this setting until seeing step change degraded performance at ~1750 rounds logged. My basis here is inline with Bart's descriptions and defining of barrel life.
At that point I re-ran my version of Berger's seating testing, and as I've found with other guns, best CBTO still held as initially determined(only now it was ~35thou OTL). The actual land relationship was way harder to lock in on by that point, but it don't matter while I'm OTL. Only best CBTO matters. The 'window' now seemed wider but did me no good as the barrel was not solid at 3/8 or better anymore, no matter what I tried. That's just what going past accurate barrel life means -when loading OTL. See, there is a price for everything. I didn't have to chase lands, but even a barrel setback won't bail me out in the end.
This gun(6.5wssm Imp) is purely a testing system. It's 16.5lb, BAT/Shethane, Border barrels, meeting Williamsport/IBS 1kyd rules. I had predicted ~1800 rounds barrel life, and had 2 barrels finished in a set. So after learning what I could about a barrel's dying, I spun it's sister barrel on, and amazingly every attribute & dimension matched perfectly. Didn't change a thing(still initial CBTO, formed cases & load) and grouping returned to 1/4moa. The brass fired in the new barrel didn't change a bit, MV didn't change. I could have swapped those barrels in the middle of a 10sht string with no detriment to the results. I have 1280 rounds on the 2nd barrel now.
I've challenged myself to understand exactly how & what seating does, and I do not know. For best OTL I'm thinking results are more to do with bullet release timing affect to peak pressure.
For best ITL, I think it's about going to another peak pressure level (a pressure node), and underbore cartridges benefit predictably here. But most hunting cartridges are not competitive underbores, so full seating testing with hunting cartridges likely leads to OTL as best. That's what I find anyway.
Also, anyone who's calibrated something(anything) knows you adjust coarse first, fine last.
Here, barring primer/striking issues, and annealing issues, it's seating first, followed by powder.
You can adjust powder to single kernels,, it's by far the finest of adjustments.
The only time it makes sense to adjust powder first is when seating is a predetermined factor.
While that's known in some conditions, most of the time(especially with hunting capacity cartridges) nothing is known until testing proves it.
What causes a barrel to go past accuracy peak, forever? Well, the ultimate killer is carbon constriction(not erosion). Carbon impinging into the metal surface profile. That's a barrel's cancer.