Berger 140g hunting VLD works for me. I killed an elk and mule deer last fall at 300 and 564 yards, respectively. I shoot high shoulder shots and the shrapnel from the first round always anchors them by severing the spinal cord and lungs. Most take a quick second round to the neck for kill shot. The deer I have killed from 300 to 500 yards using the normal shoulder shot go down between 20 to 50 yards with one shot.
I load either H4831SC or RL-17 into Lapua brass. My Shilen 24" match, select heavy hunter barrel on a Savage actions is more accurate at 2,950 fps. I am not sure but I beleive I use around 49g of powder.
Jim