dalebow, i've built both AI config. 338 06 280, to this day i've yet to find a bullet in 338 that was better than the 230 gr. failsafe for penetration , at 100 measured yds. at 2840, through 4- 1 gallon milk jugs into dirt bank 15 to 20 ft. that slug ended up weighting 229.7 loosing .3 gr. expanded .479 it just awed the heck out of me. my son ,before he went to iraq killed a cow elk running all out at 200+ yards in the valle vidal ,new mexico and told me i hit her in the neck ,my reply "git out of town" he just laughed. she piled up under a dead fall, sure enough when we got to her at the base of her neck right in front of the shoulder 338, bullet hole. those were my handloads and each gun is a law unto itself, 98 mauser action, timiney trigger,my safety 25"bbl lefthand thumb hole laminate tiger stripe stock. my wifes 280 AI loves hornady bullets i throated her chamber .100 deeper to seat the 154's drove those at 3046, i won't put my loads out there because "they are out there" if you follow me. but if you decided on either one of those calibers like several others have stated get into "handloadmode" i know a guy at the whittington center that shoots a 338-06 not an AI he handloads but only gets 2700fps much above that freezes his bolt. just my.2% my own 3006AI drives 190 horn. at 2970 i opened my mag box to 3.380 to seat them out, 180 speer g.s. are 3026fps,useing the same load for my 190s. you can't go wrong hombre. just make the choice!!!