Handloads do tilt the scale even more than with factory ammo - Generally with factory ammo, the 300 PRC with a 215 runs about 2850 where the 300 Norma runs 3010 and the 30N at 2990. We are splitting hairs and you are spot on Longshot, we can generate even more speed without SAAMI limitations. In all circumstances case capacity wins. Especially at ranges of more than 1000 yards. On steel a few more clicks in elevation isnt that big a deal but windage can be the difference between a hit and a miss.
300 PRC - 78 grains water
30N - 88 grains water
300 Norma - 104 grains water
Steel doesn't care how fast the bullet is going but for hunting in any one of these cartridges, I will always prefer faster - every single time. If all cartridges have equal accuracy then to me, every 100 or 150 or 200 fps matters when shooting an animal