The 280 AI is so easy and user friendly you can choose a whole gamut of powders and get those 160 Accubonds to 2950-3000 fps. Reloader 23 is awesome stuff if you can't find Rldr 26, but Rldr 17, H1000, Retumbo and H4831 will get you slinging 160's in the high 2900's and right at 3000 fps. 56 grains of Rldr 17 will shoot under 1 MOA at 100 and is 3020 out of my wife's 24" Kimber Montana, and 3070 out of my 26" Hart barrel. This is a hot load so start at 53 and work up. Rldr 17 is pretty temp sensitive so keep in mind about 1.5 fps/deg. F. Start at 57 grains of Rldr 23 and work up to 62 should be about max. Rldr 26 start at 61 grains and work up to 65. Try different primers too. My wifes Kimber loves CCI 250 M primers but my rifle with the Hart barrel prefers Fed 210 Match. I'm actually shooting 168 Accubond LR with 62.7 grains of Rldr 26 at 2980 and my rifle loves it! Shot a 5" group at 800 yds yesterday. Going to try at 1000 this weekend. Not too shabby when my buddy is using his 7 RUM with 89 grains of powder and getting 3030 fps. I'll take my 50 fps loss with 30% less powder all day. Ha!