I completed a 6.5 by 375 Ruger before last year's Mule deer season in Texas. Killed two deer with it at close range (120 yards or so) and it was instant results before hitting the ground. The load used a 120 g. Ballistic Tip at 3500 fps (load backed off from well over 3600 fps) and there was no grenade explosion on impact, although there was no exit. It is a Pacnor barrel and I chose one in 11 twist because I am not interested in high sectional density bullets at the cost of flatest possible tragectory to 450 yards. I pass up all longer shots and take 400 yarders only when everything appears perfect. This cartridge enables me to ignore hold over considerations for all practical shots. I put this rifle together before the introduction of the 26 Nosler and would not have bothered if I had known of the Nosler development. However, one advantage of this wildcat is I was able to do a switch barrel wit a 257 Weatherby barrel and both cartridges function through the magazine which probably will not work with the slightly fatter 26 nosler. One disadvantage to the wildcat is making the brass is a real leanring experience but once perfected, it becomes easy. Comparing published load of the 26 Nosler to my results with this wildcat might indicate that I am getting a little more velocity and/or lower pressures that the 26 Nosler because of the difference in twist rate.