I'm having a rifle built and I've pretty much settled on a .25-06. This rifle will have a 24" barrel. I have a Zeiss Conquest HD5, 3-15X42mm I'm going to mount on it. It will be used for hunting within 400 yards. I'm already set up to load .25-06. For the really long stuff I have a 26" barreled .264 Win Mag with a Leupold VX6, 3-18X50 mm. Given this info would it be worthwhile to consider the .25-06AI instead of the .25-06.
No. The standard 25-06 is very effective between 350 and 450 yards. I have taken both deer and antelope in this range with one shot kills with my 25-06. No real need for an AI at those ranges.