I shot two coyotes one night with the 75 grain Vmax no exit, which is perfect, but I never shot them again. My go to bullet was 100 grain SMK, quarter sized exit hole on chest shots. If you hit a leg bone under 300 yards it got nasty! I even head shot a few cow elk. I shot several coyotes with the 115 Berger and they worked great. Small exit wounds on coyotes and quarter sized exit on wolf at 420 yards.
My 25-06 is a 6.5-06imp now, so my stash of .257 bullets goes to my wife's 257 ackley.
Good luck