What a lot of people do not know about the Nosler ballistic tips is that from their inception they have changed over time. When they first came out many were too soft for deer size game. They just exploded on impact and deer ran off a good ways and left little to no blood trail. I started using them when they first came out and after having to crawl around in the swamps and jungle of east NC looking for deer I shot I went to other bullets. After a number of years I learned that Nosler had toughened up the HUNTING ballistic tips and I went back to give them a try. They got it right and they do a fine job when kept within their design which is, keep the impact velocity under 3100 fps. I have killed many hundred white tail deer doing crop damage control for 15 of the past 46 years of my deer hunting experience. I have killed them with about everything from a stick to a 45-70 Sharps shooting black powder and cast bullets. The 25-06 shooting most any 100 to 120 gr bullet is a killing machine. 99% of the time it is bang flop for me. The worst caliber I have ever used has been a 7mm Rem mag. I killed around 30 deer with one trying different bullet styles and weights one year and 90% would run off 100 yards or more after taking a perfect shot. I tell people that I could not carry enough flashlight batteries to hunt anymore with a 7 mm mag I had to search for deer so long in the dark. Most of my deer shooting was in the evening a little before dark. So different people have different experiences. By the way if you want a really great deer killing 25-06 bullet get you some Sierra 117 gr Pro Hunters.