Oldtime Shooter13
Well-Known Member
I have always preferred 243 over 22-250, but I am in the US. Both are accurate and depending on twist rate in both cartridges depends on bullet weight. The 22-250 will do less pelt damage depending on bullet construction. I would take a 243 in 1:10 twist for 70 to 85 grain bullets. As said in many posts if you want to shoot the heavier bullets in 243 would require 1:8 or 1:9. As far as 22-250 I prefer 1:12 twist. If you reload then either cartridge can have loads developed to do the job on a fox. IMO there is no replacement for displacements the extra that the 243 provides wins hands down.