My friend uses the 110grn V-Max, out of his 308 Winchester, for varminting. He loves it, and he has made kills all the way out to 800 yards with this bullet. It provides massive splat factor. He runs it out of his 26" barrel at around 3300fps using 53grns of Winchester 748.
I am having a rifle built around the 110grn V-Max and 125grn Ballistic Tip bullet. However, I will be using it out of specialized 300 WSM rifle called the 300 Varminter. This rifle will shoot the 125grn BT at 4000+fps out of a Bartlien 30", 1-15 twist barrel. Richard Franklin is building my rifle, and he specializes and designes high velocity rifles for varmintig. Look at his web page under Richard's Custom Rifles.
W.