When I was a kid I had a 26 inch 22-250 in high school I was given a 26 inch custom barrel 270 win. I was a hand loader for both even at a young age. I thought that I could do anything with a 22-250 until I started shooting 100 and 110 grain varmint bullets out of a 270 going 3500 - 3600 fps. I wasn't keeping pelts and with more Horse Power you can really tear up dogs. Non of this yelping and spinning in circle where you feel sorry for them. Just DRT.It's looking like a lot of 6mm flavors and some 22-250's. I like see all the calibers folks use for coyote hunting!
Keep it coming.
Later in life my buddy and went down and bought the Rem SPS varmintor 243 win 26 inch with 9 1/8th twist and it launches 87 gr. varmint bullets right at 3500 fps.
My best dog devastator round was home made 275 grain hollow points out my 26 inch 458 win mag. Exceeding 3000 fps. I will finish my story after work.