What’s your favorite caliber for deer?

I am using the .450Marlin because Ohio is a straight wall State. In NY or Mich I like the .300Wby.
 

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This year, I have several "favorites" ready for use in different scenarios. For stuff out on one of the farms in the 350-400 yard range, it will be the Cooper Jackson Game .25-06 with a 117 Sierra Gameking. Close proximity shots in my back woods, the .35 Rem (Marlin 336) will get the nod. If I'm feeling in touch with my feminine side, shooting out of the house with fuzzy slippers, it will be the Cooper Custom Classic in .243 and an 85 grain Sierra Gameking.
 
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