I know this is not the answer you are looking for but my answer is which ever one produces the best accuracy with your chosen loads. Primers do make a difference. Federal has always produced great accuracy with most loads but I have gotten great accuracy with Winchester also. I believe from my experience that Winchester primers have a bit harder cup and will handle a little more pressure than Federal. I learned NOT TO USE FEDERAL in any semi-auto that has a free floating firing pin like the M1 Garand. The cup is too thin thus making them more sensitive and they will cause slam fire. My M1 Garand was double and triple firing when I was using Federal 210 Match primers and I thought something was wrong with the rifle the first time out with it. A long time reloader and M1 shooter came over and stopped me from shooting anymore and told me without even knowing that I was using Federal primers and that was my problem. I changed to CCI and CCI BR2 and have used Rem, WW and Wolf with no problems in the M1.