the 210 will have a little less windage, and need a little more elevation. Neither will be a huge differance.. maybe 2 minutes of elevation, and a few %of windage. Honestly, you could flip a coin, they are both so close when launched from the same cartridge that theres not really much differance. For what its worth, Mine launches 220s. There wasn't that much differance in elevation between the 220SMK and the 190s, but the windage is a big improvement. Past 1k, provided the BC commensurates with the weight, the heavy bullet wins.