Iorn Worker........
I think that the Sierra 52's will be just fine, but the A max is more explosive.
I shot the Sierra 55g BTHP in my 22/250 AI on yotes. It did not tear up the yotes real bad and gave excellent penetration on quartering shots. Sierra uses the same match jacket(sorted for concentricity) on the 52 and 55g bullet.
My greatest fear was hitting a shoulder blade or a rear hip joint and the bullet blowing up, which did happen with the Speer 52g HP shot out of a 22/250 with 38.0g of H380 and a 75g Speer Hp shot out of a 6mm Rem with 46.0g of 760.
Also, don't over look the standard Sierra 55g Spt, it is a great coyote bullet.
In my 22/250 AI, 27" Hart barrel, I shot 45.5g of Win 760 with a Fed primer in Rem or PMC cases, bullets touching the lands. With this load, I usually shot around .350 @ 4150 fps.