I once thought this bullet was the cats meow for all big game, then I loaded them in my wifes 7mm-08 and she shot a 362" bull elk with that setup at 250 yards. I think impact was about 2400 fps (2850 @ barrel) and the 140 TTSX bullet barely opened up at that velocity. We almost lost that bull due to a few reasons, luckily we didn't, but the bullet not causing a large wound channel was an issue.
1800 fps seems like a acceptable min impact velocity setup for more frangible bullets, but the TTSX need to be pushed fast and hard to cause a large wound channel, I would call 2200-2400 fps the min impact for that bullet. If your looking for an all around bullet I highly recommend the original accubond, or even the partition would be better IMO.
PS, the TTSX do shoot awesome out of all rifles I loaded them in