Sound like you are somewhat like me and drawn towards the hodgdon powders. I recently picked up some Reloader 22 at sportsmans warehouse because I couldn't find any h1000 or h4831sc. I honestly couldn't be more impressed. So much so, I went back this weekend and grabbed a couple more lbs. it's fast powder... And was easy to tune a load for my 300 wm. I definitely had to back off the powder charge from what quickload recommended because velocity was 250 fps faster that QL predicted, but after that, it got me a wide node in no time at .68"... So I'm very happy. This was for the heavier 215 berger hybrids.
The only negative thing I've heard about rl22 is that it varies from lot to lot, so if you grab some and like it, get back in and get as much as you reasonable can from the same lot, otherwise you might have to work up another load once you are out of your current lot.
Good luck man!