Adding a muzzle break will defininetly change the resonant frequency of the barreled action, and therefore the harmonic frequency multiples thereof. It'll whip at a lower frequency with the weight on its muzzle. And that means bullets will leave at a different place in the muzzle's whip cycle.
Ideally, all the bullets should leave a little before the muzzle axis reaches its top; faster ones sooner than slower ones. If they leave a lot sooner, the only thing you may see is a bit more vertical shot stringing as the axis is changing its angle fastest at mid point in its swing arc.
We don't know where in your barrel's cycle bullets leave at. So, just shoot the darned thing and see what happens.