Set your rifle up on your front rest and rear bag. Pull the bolt, look down the bore at a 2" dot at 100 yards (I use the orange stick on dots on a white background since they show up real well) Make sure you keep your eye centered on the bore and the dot centered, adjust the scope....... shoot. Step two, put your crosshairs back on the target, hold the rifle steady and adjust the scope to center the crosshairs on the bullet hole. The next shot will be dead on or very close.
Using this method I can generally get my first shot to within 6 or 8 inches or less. The second shot will either be dead on or may require another 1/4 or 1/2 moa tweek.
If you will follow this formula and be careful about getting your rifle locked down in a rest / sandbags you should have no problem getting a rifle sighted with 3 to 5 shots. There is really no reason to waste time and ammo messing around at 25 yards to get on paper then moving back......