You said "feel free offer up" Here's a couple of experiences one mine and one I know of.
1) My personal experience.
Bull Winkle moose. A young one. Not much for antlers at all. Four quarters hanging in butcher shop were right at 400 lbs. Thus not a huge moose.
First shot: 60 yds broad side. Complete penetration. Saw dust where hit and on the opposite hill side. 130 gr Sierra 270 boat tail @ 3200 fps MV.
The shot severed the top of the heart from the bottom of the heart. The moose just walked off. My jaw dropped so far so fast I almost stepped on it.
A while later, longer than one would think, it fell, got back up. The next shot again @ 60 yds went through both shoulders. Again complete penetration (that bullet isn't supposed to do that).
2) Large New England moose. 30-06 factory 180s. Six shots straight on in the chest. The thing finally gave up the ghost.
Conclusions: get as much shock & awh as you can get. Just a hole completely through a moose doesn't seem to be enough from these reports and other's I have have gathered.
I'd say in the 300 with the 180 accubond souped up to the best your rifle will shot it should give you the amount of punch necessary to make a quick harvest. My moose walked about 50 yds then fell and rolled back to where I first shot him. Haul out was minimal. If he would have walked just 15 more feet the haul out would have been staggering.
I'd go with nothing less than an accubond souped up as fast as your rifle will shot it in IOM accuracy (Inches of Moose). Good shootin'