Both rifles - RL22 gave us the best velocity with 168 Bergers. Found that different lot numbers of this powder along with putting some loaded ammo in the freezer-transfer to cooler with ice and proceed to range. Shot this thru the chrony alongside identical ammo at 80F and did not like the results. We are in Montana - one week it could be 70F on the prairie chasing antelope and the next week 6-7000 feet higher and zero degrees chasing elk.
We tried Retumbo, RL19, RL22 as well as H1000 and H4831sc.
We have settled on the H4831sc in both rifles due to what we have found to be consistant for our area and our use. Both rifles have 25" Kreiger barrels. I have settled in at 2800FPS and my son is right around 2875 fps with the H4831sc.
You should have no problem reaching your desired vel with RL22 - a lot of people say there is no more temp variance with this as any other powder. The more I test temp and altitude variations the more I lean towards the H powders. If H4831sc was not available my second choice would be H1000 - But each to his own. Good luck