I've used the 168 and 180gr Bergers in my Sendero 7mm Rem Mag. They do really fly. My young son shoots MOA and better to 940yds.
We only tried the 168's initially. Once the 180's proved themselves, I see no reason to flip/flop.
He shot a whitetail at 548yds with the 180's and it was loaded down from 2900+ to a MV of 2606 fps. There was a tiny hole going in and a 3 inch exit which sucked the insides out. DRT as they say. So, it was extrememly lethal at that distance.
...ditto for wild hogs, but haven't shot any hogs at long range and we don't hunt mulies or Elk
There are many theories about terminal ballistics and lethality. Whether you're referring to a bullet that's designed to break up, or one that is designed to mushroom and retain weight, damage to vital organs is what does the trick.
Bullets usually have a minimum impact velocity or even a range in which they will expand correctly.
Comparing BC (trajectory/wind), energy, and required impact velocity, I beleive the Berger philosophy is more reliable for longer ranges than the other guys who make very good monolithic or bonded bullets.
That's my opinion based on a lot of reading and a little success.