Based on my experience the easy answer is no.The front recoil lug is a nightmare to bed,yes it can be done but ya gota make sure the screws stay at the exact same tourque or it starts wandering.
Had the local smith put an 8twist Shilen barrel chambered to 22-250 on my old Ruger tang.The bore is off so far I have to put two pieces of aluminum can material in the back base just to get it to zero.Is it the threads ,the action,the barrel???It is REAL fussy with what load it likes and is very irratic...depends on the day(it could be me for that matter)The other custom I've got(308Baer)was built by a reputable smith and shoots great but he will be the first to tell ya he would rather build on a Remington.
The other problem with a Ruger is the Scope bases,ya they work good for most applications but try to find a 20MOA base to use it for long range.
Not trying to talk you out of a Ruger,to me they are the best huntin gun going but for driveing tacks its a lot easier and cheaper to start with a Remington.
Try to find a smith with a trueing jig for a Ruger,if you find one please let me know as I've got a project for him /ubbthreads/images/graemlins/smile.gif