I shoot 70grs of Retumbo with 140 Amax's in RWS brass at 3230fps (its a pretty hot load in my gun). I've also shot 73grs of R-33 at 3290fps. With Winchester brass you can add about 2.5-3grs of powder and 50+fps. That is a 28" Bartlein barrel. In my 26" barreled gun I shoot 73grs of Retumbo with 123 Amax's in RWS brass at 3380fps. It's hell on rockchucks.
I'll probably play with some R-50 and R-33 loads in the next little bit with my newest 6.5-300wm using Winchester brass to see what kind of velocity I can get with 123's and 140's. IMO Retumbo is really too fast for the case capacity and R-33 might be too fast with 140's as well. My Retumbo loads are just 1/4"-3/8" loads so I hate to burn a barrel up playing too much.