I don't know what this guy is writing about, but as always someone has a opinions and strongly (sometimes abrasively) expresses them. Reloading for 40+ years and for me reloading for 57 years, that doesn't make me an expert, and there's always room for improvement and for learning. With that said I have one of those "ole Rockchucker" presses that I have had for at least thirty-years!!! And.....that "ole press" like the "ole owner" has never had a problem with "ANY" caliber that it has had reloaded on it. I have never reloaded the 338-378, however I did check the COAL of the cartridge; 3.763 inches; Nosler #8. I compared that cartridge with a 300 WinMag (this one I have loaded) and it has a COAL of 3.560, thus there is a .203 thousandths of an inch difference. I don't need to go to my basement to see if it will fit. This "ole" owner has loaded so many cartridges on this "ole" press, he knows that loading the 338-378 is not going to be impossible to reload due to a .203 thousandths of an inch difference. As for comparing a "C" press to an "O" press I will put the "O" press up against one ("C" press) anytime for strength, accuracy, repeatability, ease of use and durability!! Dracer you've had several other posts suggesting a different press. The press you have "ought" to work. I'm not sure, however my experience with a turret press is that it will get the job done, it just isn't as rugged, strong and as accurate as an "O" press; Rockchucker or similar "O" presses. The more that you turn the turret the more it will wear and after a while the die plate will get sloppy. When you full-length resize your cases the resistance of the outside of the casing inside of the resizing die will put a lot of pressure on the die plate and the die plate will bend/move back away from the ram on your press. This will in turn move the center of your die and the center of your shell holder/press-ram out of alignment. There's a lot of surface that has to be moved and reshaped with the 338-378, and as such it will put a lot of strain on the press due to the resistance of the casing on the inside of the die when you full-length resize your cases. In a previous response I wrote that your press ought to work just fine on your 32 Special and your 35 Remington cases, however you are asking a lot of your press when you step up to the 338-378, that's one of the granddaddies of cartridges!! You've got a lot of information to digest, good luck with any decision that you make.