I ended up backing off more than a full grain due to temp sensitivity in 33. When it's a cool spring day, my max load is 102.3. When the sun is out, no way can I shoot 102.3. It went down 101.3 to be safe. 33 is a unbelievable powder, but it does have its draw backs. Temp being the major one. Here's a thread that can give you lots of examples of this.
http://www.longrangehunting.com/forums/f19/rl33-temperature-regression-thread-130521/