Have had good results with r19 and 168 bergers. 58 grains in my gun is max! And pokes .5" very consistently 2975-3000fps until its 85+ degrees outside. Then it opens a bit. Nosler #6 max is 59gr. Traditionally a good powder for 280 and 280ai. 140 accubonds in front of around 60 gr r19 good too.