Yes. I believe it can. I an using a 270 for a magnum build.
There will be some additional work.
Bolt/bolt face. From Standard to Magnum.
Feed lips will need to be widened.
and I would say go for it.
but to add a little discussion.
What are you after for ballistics?
The 26-Nosler is seriously impressive but I put it in the class if a 7mmRUM. This from a 300RUM and 338/300RUM shooter. It's very fast but you have to remember that barrels are a consumable portion of the shooting process.
I will soon have a 270/26-Nosler, 284/26-Nosler, 308/26-Nosler and 338/26-Nosler. So of course I support anyone wanting to go the route of a 26-Nosler anything. Though for myself I will skip the actual 26-Nosler chambering.
If you want the fasted 6.5mm, to quote Michael Myers "Yeah baby". Just remember the barrel may not last as long as your 30-06.
A suggestion: rechamber your 30-06 to 308/26-Nosler. It will be more than a Win Mag or WSM but not as much as a 300RUM. The efficiency is according to QuickLoad is better than a 300RUM so it might not be less than a RUM in the end.